antifungal drugs

Current status and future development of antifungal drugs

抗真菌药的近况与开发

Progress in research of antifungal drugs and its interaction

抗真菌药与药物相互作用研究进展

Conclusions Candida species display different resistance to five antifungal drugs .

结论不同念珠菌对常用抗真菌药物敏感性存在差异，准确分离鉴定和药敏试验，对于指导临床合理选药有重要意义。

Main Outcome Measures The minimum inhibitory concentration of antifungal drugs .

主要指标药物最低抑菌浓度。

Susceptibility testing of Candida species to five antifungal drugs The Antimicrobial Drugs

临床分离念珠菌对5种常用抗真菌药物的体外敏感试验结果分析

Thirty-seven cases were dead among the 94 cases being treated with antifungal drugs .

94例经抗真菌治疗者中37例死亡。

Susceptibility Testing of 28 Strains of Yeasts to the Combination of Antifungal Drugs in vitro

28株酵母菌的体外联合药敏试验分析

Even when treated with antifungal drugs , the infection may take several weeks to disappear and may come back after treatment .

即使使用抗真菌药物，感染可能也要花上几个星期才会消失，并可能在治疗后复发。

Three patients died among 17 patients being treated with antifungal drugs , while all 6 patients died without antifungal therapy .

17例经抗真菌治疗者3例死亡，而6例未治疗者均死亡。

Contact dermatitis due to some topical imidazole antifungal drugs

几种咪唑类外用抗真菌药接触性皮炎的初步研究

Oral Isolates of Saccharomyces in Patients with Oral Fungal Infection and Their Susceptibility to Antifungal Drugs

口腔念珠菌病患者口内菌株的检出和药敏性观察

In vitro susceptibility of Cryptococcus neoformans and Candida species to five antifungal drugs

新型隐球菌及念珠菌临床分离株对5种抗真菌药物的体外敏感性

Assaying the Susceptibility of Fluconazole-Resistant Candida Albicans to Common Antifungal Drugs

耐氟康唑的白念珠菌对常见抗真菌药物的敏感性检测

In summary , this study has great significance for the action mechanism research of echinocandins and the development of the new type antifungal drugs .

本研究对新型棘白菌素类抗真菌药物的作用机理研究和新药开发有重大意义。

Agar dilution screening for drug susceptibility with the current panel of antifungal drugs is rapid , accurate and effective .

琼脂稀释法对于筛查当前抗真菌药物敏感性是快速、准确、有效的。

In vitro susceptibility test of Cryptococcus neoformans isolated from cryptococcal meningitis to antifungal drugs

隐球菌性脑膜炎感染菌株对抗真菌药物的体外敏感性检测

Currently , reasonable individualized treatments for patients are realizable for much more types of antifungal drugs are available in clinic .

目前临床已有较丰富的抗真菌药物以供选择，有利于合理的个体化用药。

Study on Pathogenicity , Susceptibility to Antifungal Drugs and Electrophoretic Karyotype of Uncommon Pathogenic Yeasts

临床少见致病酵母的致病力和体外药物敏感性及电泳核型的初步研究

Methods The broth microdilution method was performed to determined the minimal inhibitory concentration of 4 antifungal drugs to 20 candida albicans .

方法：微量稀释法测定4种抗真菌药物对20株白念珠菌的最低抑菌浓度（MinimalInhibitoryConcentration，MIC）；

Assessment of resistance was based on growth characteristics , wherein decreased colony size in the presence of antifungal drugs was used as an indicator of susceptibility .

耐药性的评估基于生长特性，抗真菌药物存在时菌落大小缩小被视为敏感性的指标。

The susceptibility of fungus to nystatin was the highest ( 96 % ) in the antifungal drugs tested .

在所测抗真菌药中，酵母样真菌对制菌霉素的敏感性最高（95%）。

Objective To investigate the pathogenicity , susceptibility to antifungal drugs , and electrophoretic karyotype of clinically uncommon pathogenic yeasts .

目的比较10种临床少见酵母致病力的大小，体外对抗真菌药物敏感性的高低以及电泳核型的差异。

OBJECTIVE To understand flora distribution and four antifungal drugs ′ in vitro antifungal activity of deep fungi in nosocomial infection in order to provide help to clinics .

目的了解医院感染患者深部真菌感染的菌群分布及4种抗真菌药物的体外抗菌活性，为临床合理应用抗真菌药物提供帮助。

Furthermore , verapamil inhibited hyphal development , biofilm formation and biofilm maintenance , and enhanced the inhibitory effect of antifungal drugs against biofilms .

在形态发生方面，verapamil能够明显抑制白念珠菌菌丝及生物被膜发育，并且能够增强抗真菌药物对生物被膜形成与维持的抑制作用。

There is still a broad market for the development of antifungal drugs , especially the low toxicity , high efficiency , and the broad-spectrum antifungal drugs , even broader space .

抗真菌药物仍存在宽广的发展市场，特别是低毒、高效和广谱的抗真菌药物的发展空间更为广阔，未来的真菌市场仍然是知名品牌占主导地位。

We examined the utility of agar dilution to screen yeasts for reduced susceptibility to several newer antifungal drugs including echinocandins and azoles .

我们研究了琼脂稀释法筛选对多种新型抗真菌药物包括棘白菌素和唑类敏感性降低酵母菌的实用性。

The E test is a brief and quick assay for IT and FL susceptibility testing of vaginal pathogenic yeast , and it is a useful method clinically for selecting effective antifungal drugs .

E-test法检测酵母菌对IT、FL的敏感性具有操作简便、快速的特点，为临床选择抗真菌药物具有一定的意义。

Fungal infection especially deep infection has threatened the human health seriously . With the extensive use of antifungal drugs , more and more resistant strains emerged , looking for new antifungal agents become imperative .

真菌感染尤其是深部感染已经给人类健康带来了严重威胁，而随着抗真菌药物的大量使用，越来越多的菌株出现了耐药性，寻找新型抗真菌药物成为当务之急。

METHODS : According to the relevant parameters of antifungal drugs market and their clinical application in hospitals in national medicine economical information network during 2002 ~ 2004 , the related literature at home and abroad was reviewed and analyzed .

方法：根据国内权威医药经济信息网站2002年~2004年有关抗真菌药市场和医院临床应用的数据，结合国内、外医药文献进行综述和分析。

Moreover , This fungus evolved an elaborate stress response system to sense environmental stimuli , such as antifungal drugs , oxidative agents and nutrient depletion , and to respond to them for survival and growth .

不仅如此，白念珠菌还具有极为精细的环境压力应答系统，用以感应抗真菌药物、氧化胁迫、营养匮乏等诸多环境压力，并对其作用应答，使自身得以存活与生长。